Conclusions: Three key subelements, nt453-434, nt403-384 and nt283-264 sequence, were successfully identified in the negative regulatory element on hepatitis B virus.
結(jié)論:HBV nt453-434、nt403-384和nt283-264序列爲HBV nt250-453負性調(diào)節(jié)元件中發(fā)揮關(guān)鍵作用的三個亞元件;這三個亞元件可以獨立發(fā)揮作用;儅以協(xié)同的方式發(fā)揮作用時,則表現(xiàn)出最強的負性調(diào)節(jié)作用。